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Warfarin's less potent R-enantiomer is metabolized in part by CYP3A4 (and in addition CYP1A2 and CYP2C19). Monitor INR more regularly if coadministered with inhibitors of those isoenzymes and change warfarin dose if desired.A 2020 assessment described that modafinil contains a modest impact on memory updating, but the effect is small and will not p

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